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SEC FORM 4 SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940 		 
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
FHM IV LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [ FOLD ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director X 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
02/12/2008
4. If Amendment, Date of Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
X Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/13/2008 P 800 A $10.44 624,667 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 300 A $10.45 624,967 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 600 A $10.46 625,567 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 100 A $10.47 625,667 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 100 A $10.48 625,767 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 900 A $10.49 626,667 I By Frazier Healthcare V, LP(1)(2)
Common Stock 02/13/2008 P 3,000 A $10.5 629,667 I By Frazier Healthcare V, LP(1)(2)
Common Stock 2,586,886 I By Frazier Healthcare IV, LP(2)(3)
Common Stock 13,128 I By Frazier Affiliates IV, LP(2)(3)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
1. Name and Address of Reporting Person*
FHM IV LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
1. Name and Address of Reporting Person*
Frazier Healthcare V, LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
1. Name and Address of Reporting Person*
FHM V, LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
1. Name and Address of Reporting Person*
FHM V, LLC
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
1. Name and Address of Reporting Person*
FRAZIER HEALTHCARE IV LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
1. Name and Address of Reporting Person*
FRAZIER AFFILIATES IV LP
(Last) (First) (Middle)
601 UNION STREET, SUITE 3200
(Street)
SEATTLE WA 98101
(City) (State) (Zip)
Explanation of Responses:
1. The securities are owned directly by Frazier Healthcare V, LP. FHM V, LP, a joint filer, servesas the general partner of Frazier Healthcare V, LP and FHM V, LLC, serves as the general partner of FHM V, LP. FHM V, LP and FHM V, LLC disclaim beneficial ownership of the reported securities except to the extent of their pecuniary interest therein.
2. There is no direct relationship among or between FHM V, LLC, FHM V, L.P. and Frazier Healthcare V, L.P., on the one hand, and FHM IV, LP, Frazier Healthcare IV, LP and Frazier Affiliates IV, LP, on the other. Beneficial ownership of Issuer shares as described herein and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purposes of Section 16 or for any other purpose.
3. The securities are owned directly by the entity listed. Frazier Healthcare IV, LP and Frazier Affiliates IV, LP are joint filers. The designated filer, FHM IV, LP, serves as the general partner of Frazier Healthcare IV, LP and Frazier Affiliates IV, LP. FHM IV, LP disclaims beneficial ownership of the reported securities, except to the extent of its proportionate pecuniary interest therein.cuniary interest therein.
Remarks:
Exhibit 99.1 - Joint Filer Information
FHM IV, LP, By: FHM IV, LLC, its General Partner, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
Frazier Healthcare V, LP, By: FHM V, LP, its General Partner, By: FHM V, LLC, its General Partner, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
FHM V, LP, By: FHM V, LLC, its General Partner, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
FHM V, LLC, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
Frazier Healthcare IV, LP, By: FHM IV, LP, its General Partner, By: FHM IV, LLC, its General Partner, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
Frazier Affiliates IV, LP, By: FHM IV, LP, its General Partner, By: FHM IV, LLC, its General Partner, By: /s/ Thomas S. Hodge, Chief Operating Officer 02/14/2008
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
Exhibit 99.1
Form 4 Joint Filer Information

Name:                           Frazier Healthcare V, LP

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:  February 12, 2008

                  Frazier Healthcare V, LP
                  By: FHM V, LP, its General Partner
                  By: FHM V, LLC, its General Partner


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer


Name:                           FHM V, LP

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:  February 12, 2008

                  FHM V, LP
                  By: FHM V, LLC, its General Partner


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer


Name:                           FHM V, LLC

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:  February 12, 2008

                  FHM V, LLC


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer



Name:                           Frazier Healthcare IV, LP

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:  February 12, 2008

                  Frazier Healthcare IV, LP
                  By: FHM IV, LP, its General Partner
                  By: FHM IV, LLC, its General Partner


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer


Name:                           Frazier Affiliates IV, LP

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:   February 12, 2008

                  Frazier Affiliates IV, LP
                  By: FHM IV, LP, its General Partner
                  By: FHM IV, LLC, its General Partner


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer


Name:                           FHM IV, LP

Address:                        601 Union Street, Suite 3200, Seattle, WA 98101

Designated Filer:               FHM IV, LP

Issuer & Ticker Symbol:         Amicus Therapeutics, Inc. (FOLD)

Date of Event Requiring Statement:   February 12, 2008

                  FHM IV, LP
                  By: FHM IV, LLC, its General Partner


                  By:      /s/ Thomas S. Hodge
                      Thomas S. Hodge,
                      Chief Operating Officer