================================================================================


                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                  SCHEDULE 13D

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                              (AMENDMENT NO. ___)*


                            Amicus Therapeutics, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                          Common Stock, $.01 par value
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    03152W109
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                              Louis S. Citron, Esq.
                            New Enterprise Associates
                    1119 St. Paul Street, Baltimore, MD 21202
                                 (410) 246-2927
--------------------------------------------------------------------------------
       (Name, Address and Telephone Number of Person Authorized to Receive
                           Notices and Communications)

                                  July 25, 2007
--------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of ss.ss.240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box.

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See ss.240.13d-7 for other
parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
================================================================================

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 2 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       New Enterprise Associates 9, Limited Partnership
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       WC
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       PN
================================================================================

                               Page 2 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 3 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       NEA Partners 9, Limited Partnership
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       PN
================================================================================

                               Page 3 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 4 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       New Enterprise Associates 11, Limited Partnership
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       WC
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       PN
================================================================================

                               Page 4 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 5 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       NEA Partners 11, Limited Partnership
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       PN
================================================================================

                               Page 5 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 6 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       NEA 11 GP, LLC
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       Delaware
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       PN
================================================================================

                               Page 6 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 7 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Michael James Barrett
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 7 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 8 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Peter J. Barris
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 8 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 9 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Forest Baskett
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 9 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 10 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Ryan D. Drant
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 10 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 11 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Krishna Kolluri
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 11 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 12 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       C. Richard Kramlich
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 12 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 13 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Charles M. Linehan
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 13 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 14 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Charles W. Newhall III
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 14 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 15 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Mark W. Perry
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            4,510,340 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        4,510,340 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       4,510,340 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       20.3%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 15 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 16 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Scott D. Sandell
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 16 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 17 OF 30 PAGES
===================                                          ===================

================================================================================
  1    NAMES OF REPORTING PERSONS.
       I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY).

       Eugene A. Trainor III
-----  -------------------------------------------------------------------------
  2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)(a)[_]
                                                                          (b)[_]

-----  -------------------------------------------------------------------------
  3    SEC USE ONLY


-----  -------------------------------------------------------------------------
  4    SOURCE OF FUNDS (SEE INSTRUCTIONS)

       AF
-----  -------------------------------------------------------------------------
  5    CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
       ITEMS 2(d) or 2(e)  [_]

-----  -------------------------------------------------------------------------
  6    CITIZENSHIP OR PLACE OF ORGANIZATION

       United States citizen
--------------------------------------------------------------------------------
                   7    SOLE VOTING POWER

                        0 shares
                 -----  --------------------------------------------------------
  NUMBER OF        8    SHARED VOTING POWER
   SHARES
BENEFICIALLY            3,659,157 shares
  OWNED BY       -----  --------------------------------------------------------
    EACH           9    SOLE DISPOSITIVE POWER
  REPORTING
   PERSON               0 shares
    WITH         -----  --------------------------------------------------------
                  10    SHARED DISPOSITIVE POWER

                        3,659,157 shares
-----  -------------------------------------------------------------------------
 11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

       3,659,157 shares
-----  -------------------------------------------------------------------------
 12    CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
       (SEE INSTRUCTIONS)                                                    [_]

-----  -------------------------------------------------------------------------
 13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

       16.5%
-----  -------------------------------------------------------------------------
 14    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

       IN
================================================================================

                               Page 17 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 18 OF 30 PAGES
===================                                          ===================

                                  Schedule 13D

Item 1. Security and Issuer.
        -------------------

     This statement relates to the common stock, $.01 par value (the "Common
Stock") of Amicus Therapeutics, Inc. (the "Issuer") having its principal
executive office at 6 Cedar Brook Drive, Cranbury, New Jersey 08512.

Item 2. Identity and Background.
        -----------------------

     This statement is being filed by:

     (a) New Enterprise Associates 9, Limited Partnership ("NEA 9") and New
Enterprise Associates 11, Limited Partnership ("NEA 11" and, together with NEA
9, being collectively referred to herein as the "Funds" or the "Record
Holders");

     (b) NEA Partners 9, Limited Partnership ("NEA Partners 9"), which is the
sole general partner of NEA 9; NEA Partners 11, Limited Partnership ("NEA
Partners 11" and, together with NEA Partners 9, the "GPLPs"), which is the sole
general partner of NEA 11; and NEA 11 GP, LLC ("NEA 11 LLC" and, together with
the GPLPS, the "Control Entities"), which is the sole general partner of NEA
Partners 11; and

     (c) Michael James Barrett ("Barrett"), Peter J. Barris ("Barris"), Forest
Baskett ("Baskett"), Ryan D. Drant ("Drant"), Krishna Kolluri ("Kolluri"), C.
Richard Kramlich ("Kramlich"), Charles M. Linehan ("Linehan"), Charles W.
Newhall III ("Newhall"), Mark W. Perry ("Perry"), Scott D. Sandell ("Sandell")
and Eugene A. Trainor III ("Trainor" and together with Barrett, Barris, Baskett,
Drant, Kolluri, Kramlich, Linehan, Newhall, Perry and Sandell, the "Managers").

     Barris, Kramlich, Newhall and Perry (the "Senior Managers") are individual
general partners of NEA Partners 9 and are individual members of NEA 11 LLC.
Barrett, Baskett, Drant, Kolluri, Linehan, Sandell and Trainor are individual
members of NEA 11 LLC.

     The persons named in this Item 2 are referred to individually herein as a
"Reporting Person" and collectively as the "Reporting Persons."

     The address of the principal business office of each Record Holder, each
Control Entity, Barrett, Drant, Newhall and Trainor is New Enterprise
Associates, 1119 St. Paul Street, Baltimore, Maryland 21202. The address of the
principal business office of Baskett, Kolluri, Kramlich, Linehan, Perry and
Sandell is New Enterprise Associates, 2490 Sand Hill Road, Menlo Park,
California 94025. The address of the principal business office of Barris is One
Freedom Square, 11951 Freedom Drive, Suite 1240, Reston, Virginia 20190.

     The principal business of each Fund is to invest in and assist
growth-oriented businesses located principally in the United States. The
principal business of NEA Partners 9 is to act as the sole general partner of
NEA 9. The principal business of NEA Partners 11 is to act as the sole general
partner of NEA 11. The principal business of NEA 11 LLC is to act as the sole
general partner of NEA Partners 11. The principal business of each of the
Managers is to manage the Control Entities, the Funds and a number of affiliated
partnerships with similar businesses.

     During the five years prior to the date hereof, none of the Reporting
Persons has been convicted in a criminal proceeding or has been a party to a
civil proceeding ending in a judgment, decree or final order enjoining future
violations of, or prohibiting or mandating activities subject to, federal or
state securities laws or finding any violation with respect to such laws.

                               Page 18 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 19 OF 30 PAGES
===================                                          ===================

     Each Fund and each GPLP is a limited partnership organized under the laws
of the State of Delaware. NEA 11 LLC is a limited liability company organized
under the laws of the State of Delaware. Each of the Managers is a United States
citizen.

Item 3. Source and Amount of Funds or Other Consideration.
        -------------------------------------------------

     Between May 4, 2004 and March 12, 2007 NEA 11 purchased (i) 7,430,982
shares of series B redeemable convertible preferred stock of the Issuer ("Series
B Stock"), (ii) a warrant to purchase 113,083 shares of Series B Stock of the
Issuer, (iii) 7,621,664 shares of series C redeemable convertible preferred
stock of the Issuer ("Series C Stock"), and (iv) 12,326,048 shares of series D
redeemable convertible preferred stock of the Issuer ("Series D Stock" and,
together with Series B Stock and Series C Stock, "Preferred Stock") for an
aggregate purchase price of $35,928,507.46. As a result of a 1:7.5 reverse stock
split (the "Stock Split") that became effective on May 24, 2007, every 7.5
shares of the Issuer's Preferred Stock were combined into one share of the
Issuer's Preferred Stock. Upon closing of the Issuer's May 30, 2007 initial
public offering (the "IPO"), the Issuer's Preferred Stock automatically
converted into shares of Common Stock on a one for one basis. In addition, upon
the closing of the IPO, the warrants to purchase Series B Stock were
automatically exercised and the shares of Series B Stock automatically converted
into shares of Common Stock on a one for one basis. As a result of the Stock
Split and the IPO, NEA 11's Preferred Stock and warrants to purchase Series B
Stock (net of the purchase price thereof) were automatically converted into
3,659,157 shares of the Issuer's Common Stock (the "NEA 11 Shares").

     Between September 13, 2006 and March 12, 2007 NEA 9 purchased 6,163,024
shares of Series D Stock for an aggregate purchase price of $9,999,999.48. As a
result of the Stock Split and the IPO, NEA 9's Preferred Stock was automatically
converted into 821,736 shares of the Issuer's Common Stock. On July 25, 2007,
NEA 9 acquired an additional 29,447 shares of Common Stock for an aggregate
purchase price of $338,452.03. NEA 9 now holds a total of 851,183 shares of the
Issuer's Common Stock (the "NEA 9 Shares" and, together with the NEA 11 shares,
the "Firm Shares").

     The working capital of NEA 9 was the source of the funds for the purchase
of the NEA 9 Shares and the working capital of NEA 11 was the source of the
funds for the purchase of the NEA 11 Shares. No part of the purchase price of
the Firm Shares was represented by funds or other consideration borrowed or
otherwise obtained for the purpose of acquiring, holding, trading or voting the
Firm Shares.


Item 4. Purpose of Transaction.
        ----------------------

     The Funds acquired the Firm Shares for investment purposes. Depending on
market conditions, its continuing evaluation of the business and prospects of
the Issuer and other factors, NEA 9, NEA 11 and other Reporting Persons may
dispose of or acquire additional shares of the Issuer. Except as set forth
above, none of the Reporting Persons has any present plans which relate to or
would result in:

     (a)  The acquisition by any person of additional securities of the Issuer,
          or the disposition of securities of the Issuer;

     (b)  An extraordinary corporate transaction, such as a merger,
          reorganization or liquidation, involving the Issuer or any of its
          subsidiaries;

     (c)  A sale or transfer of a material amount of assets of the Issuer or any
          of its subsidiaries;

     (d)  Any change in the present board of directors or management of the
          Issuer, including any plans or proposals to change the number or term
          of directors or to fill any existing vacancies on the board;

     (e)  Any material change in the present capitalization or dividend policy
          of the Issuer;

                               Page 19 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 20 OF 30 PAGES
===================                                          ===================

     (f)  Any other material change in the Issuer's business or corporate
          structure;

     (g)  Changes in the Issuer's charter, bylaws or instruments corresponding
          thereto or other actions which may impede the acquisition of control
          of the Issuer by any person;

     (h)  Causing a class of securities of the Issuer to be delisted from a
          national securities exchange or to cease to be authorized to be quoted
          in an inter-dealer quotation system of a registered national
          securities association;

     (i)  A class of equity securities of the Issuer becoming eligible for
          termination of registration pursuant to Section 12(g)(4) of the
          Securities Exchange Act of 1934; or

     (j)  Any action similar to any of those enumerated above.


Item 5. Interest in Securities of the Issuer.
        ------------------------------------

          NEA 9 is the record owner of the NEA 9 Shares. As the sole general
          partner of NEA 9, NEA Partners 9 may be deemed to own beneficially the
          NEA 9 Shares. NEA 11 is the record owner of the NEA 11 Shares. As the
          sole general partner of NEA 11, NEA Partners 11 may be deemed to own
          beneficially the NEA 11 Shares. As the sole general partner of NEA
          Partners 11, NEA 11 LLC may be deemed to own beneficially the NEA 11
          Shares.

          By virtue of their relationship as affiliated entities, whose Control
          Entities have overlapping individual controlling persons, each of the
          Record Holders may be deemed to share the power to direct the
          disposition and vote of the Firm Shares. As general partners of the
          Funds, each of the GPLPs may also be deemed to own beneficially the
          Firm Shares. As the sole general partner of NEA Partners 11, NEA 11
          LLC may also be deemed to own beneficially the Firm Shares.

          As individual general partners of NEA Partners 9 and members of NEA 11
          LLC, each of the Senior Managers may be deemed to own beneficially all
          of the Firm Shares. As members of NEA 11 LLC, each of Barrett,
          Baskett, Drant, Kolluri, Linehan, Sandell and Trainor may be deemed to
          own beneficially the NEA 11 Shares.

          Each Reporting Person disclaims beneficial ownership of the Firm
          Shares other than those shares which such person owns of record.

          The percentage of outstanding Common Stock of the Issuer which may be
          deemed to be beneficially owned by each Reporting Person is set forth
          on Line 13 of such Reporting Person's cover sheet. Such percentage was
          calculated based on the 22,234,426 shares of Common Stock reported to
          be outstanding after the IPO, as reported on the Issuer's Form 424B4,
          filed with the Securities Exchange Commission on May 31, 2007.

     (b) Regarding the number of shares as to which such person has:

          (i)  sole power to vote or to direct the vote: See line 7 of cover
               sheets

          (ii) shared power to vote or to direct the vote: See line 8 of cover
               sheets

          (iii) sole power to dispose or to direct the disposition: See line 9
               of cover sheets.

          (iv) shared power to dispose or to direct the disposition: See line 10
               of cover sheets

                               Page 20 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 21 OF 30 PAGES
===================                                          ===================

     (c)  Except as set forth in Item 3 above, none of the Reporting Persons has
          effected any transaction in the Common Stock during the last 60 days.

     (d)  No other person is known to have the right to receive or the power to
          direct the receipt of dividends from, or any proceeds from the sale
          of, Shares beneficially owned by any of the Reporting Persons.

     (e)  Not Applicable.

Item 6. Contracts, Arrangements, Undertakings or Relationships with Respect to
        ----------------------------------------------------------------------
        Securities of the Issuer.
        ------------------------ 
        
     Not applicable.

Item 7. Material to be Filed as Exhibits.
        --------------------------------

     Exhibit 1 - Agreement regarding filing of joint Schedule 13D.

     Exhibit 2 - Power of Attorney regarding Schedule 13D filings.


















                               Page 21 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 22 OF 30 PAGES
===================                                          ===================

                                   SIGNATURE

     After reasonable inquiry and to the best of its knowledge and belief, each
of the undersigned certifies that the information set forth in this statement is
true, complete and correct.

Date: August 7, 2007


NEW ENTERPRISE ASSOCIATES 9,
LIMITED PARTNERSHIP

By:  NEA PARTNERS 9, LIMITED PARTNERSHIP
     General Partner

     By:              *                                           
         -------------------------
         Charles W. Newhall III
         General Partner


NEA PARTNERS 9, LIMITED PARTNERSHIP


By:          *                                      
     -------------------------
     Charles W. Newhall III
     General Partner


NEW ENTERPRISE ASSOCIATES 11,
  LIMITED PARTNERSHIP

By:  NEA PARTNERS 11, LIMITED PARTNERSHIP
     General Partner

     By: NEA 11 GP, LLC
         General Partner


         By:             *                                               
             ------------------------
             Eugene A. Trainor III
             Administrative Manager


NEA PARTNERS 11, LIMITED PARTNERSHIP

By:  NEA 11 GP, LLC
     General Partner

     By:            *                                                         
         ------------------------
         Eugene A. Trainor III
         Administrative Manager


                               Page 22 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 23 OF 30 PAGES
===================                                          ===================

NEA 11 GP, LLC


By:            *                                                           
    ------------------------
    Eugene A. Trainor III
    Administrative Manager


         *               
-------------------------
Michael James Barrett


         *               
-------------------------
Peter J. Barris


         *               
-------------------------
Forest Baskett


         *               
-------------------------
Ryan D. Drant


         *               
-------------------------
Krishna Kolluri


         *               
-------------------------
C. Richard Kramlich


         *               
-------------------------
Charles M. Linehan


         *               
-------------------------
Charles W. Newhall III


         *               
-------------------------
Mark W. Perry


         *               
-------------------------
Scott D. Sandell


         *               
-------------------------
Eugene A. Trainor III

                               Page 23 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 24 OF 30 PAGES
===================                                          ===================

                                 */s/ Louis S. Citron                           
                                 ------------------------
                                 Louis S. Citron
                                 As attorney-in-fact


This Schedule 13D was executed by Louis S. Citron on behalf of the individuals
listed above pursuant to a Power of Attorney a copy of which is attached as
Exhibit 2.





























                               Page 24 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 25 OF 30 PAGES
===================                                          ===================

                                                                       EXHIBIT 1
                                                                       ---------

                                    AGREEMENT

     Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the
undersigned hereby agree that only one statement containing the information
required by Schedule 13D need be filed with respect to the ownership by each of
the undersigned of shares of stock of Amicus Therapeutics, Inc.

EXECUTED this 7th day of August, 2007.


NEW ENTERPRISE ASSOCIATES 9,
  LIMITED PARTNERSHIP

By:  NEA PARTNERS 9, LIMITED PARTNERSHIP
     General Partner

     By:            *                                           
         -------------------------
         Charles W. Newhall III
         General Partner


NEA PARTNERS 9, LIMITED PARTNERSHIP


By:           *                                      
     -------------------------
     Charles W. Newhall III
     General Partner


NEW ENTERPRISE ASSOCIATES 11,
  LIMITED PARTNERSHIP

By:  NEA PARTNERS 11, LIMITED PARTNERSHIP
     General Partner

     By: NEA 11 GP, LLC
         General Partner


         By:            *                                               
             ------------------------
             Eugene A. Trainor III
             Administrative Manager

                               Page 25 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 26 OF 30 PAGES
===================                                          ===================

NEA PARTNERS 11, LIMITED PARTNERSHIP

By:  NEA 11 GP, LLC
     General Partner


By:           *                                                                 
    ------------------------
    Eugene A. Trainor III
    Administrative Manager


NEA 11 GP, LLC

By:           *                                                           
    ------------------------
    Eugene A. Trainor III
    Administrative Manager


         *               
-------------------------
Michael James Barrett


         *               
-------------------------
Peter J. Barris


         *               
-------------------------
Forest Baskett


         *               
-------------------------
Ryan D. Drant


         *               
-------------------------
Krishna Kolluri


         *               
-------------------------
C. Richard Kramlich


         *               
-------------------------
Charles M. Linehan


         *               
-------------------------
Charles W. Newhall III


         *               
-------------------------
Mark W. Perry

                               Page 26 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 27 OF 30 PAGES
===================                                          ===================


         *               
-------------------------
Scott D. Sandell


         *               
-------------------------
Eugene A. Trainor III



                                         */s/ Louis S. Citron                   
                                         ------------------------
                                         Louis S. Citron
                                         As attorney-in-fact


This Agreement relating to Schedule 13D was executed by Louis S. Citron on
behalf of the individuals listed above pursuant to a Power of Attorney a copy of
which is attached hereto as Exhibit 2.


















                               Page 27 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 28 OF 30 PAGES
===================                                          ===================

                                                                       EXHIBIT 2
                                                                       ---------

                                POWER OF ATTORNEY

     KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes and
appoints Charles W. Newhall III, Louis S. Citron, Eugene A. Trainor III and
Shawn Conway, and each of them, with full power to act without the others, his
true and lawful attorney-in-fact, with full power of substitution, to sign any
and all instruments, certificates and documents that may be necessary, desirable
or appropriate to be executed on behalf of himself as an individual or in his
capacity as a direct or indirect general partner, director, officer or manager
of any partnership, corporation or limited liability company, pursuant to
section 13 or 16 of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), and any and all regulations promulgated thereunder, and to file
the same, with all exhibits thereto, and any other documents in connection
therewith, with the Securities and Exchange Commission, and with any other
entity when and if such is mandated by the Exchange Act or by the By-laws of the
National Association of Securities Dealers, Inc., granting unto said
attorney-in-fact full power and authority to do and perform each and every act
and thing necessary, desirable or appropriate, fully to all intents and purposes
as he might or could do in person, thereby ratifying and confirming all that
said attorney-in-fact, or his substitutes, may lawfully do or cause to be done
by virtue hereof.

     IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 30th
day of March, 2007.


                                   /s/ Forest Baskett
                                   --------------------------
                                   Forest Baskett


                                   /s/ M. James Barrett
                                   --------------------------
                                   M. James Barrett


                                   /s/ Peter J. Barris
                                   --------------------------
                                   Peter J. Barris


                                   /s/ Ryan Drant
                                   --------------------------
                                   Ryan Drant


                                   /s/ Shawn Conway
                                   --------------------------
                                   Shawn Conway


                                   /s/ Paul Hsiao
                                   --------------------------
                                   Paul Hsiao


                                   /s/ Vladimir Jacimovic
                                   --------------------------
                                   Vladimir Jacimovic


                                   /s/ Patrick J. Kerins
                                   --------------------------
                                   Patrick J. Kerins


                               Page 28 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 29 OF 30 PAGES
===================                                          ===================

                                   /s/ Suzanne King
                                   --------------------------
                                   Suzanne King


                                   /s/ Krishna S. Kolluri
                                   --------------------------
                                   Krishna S. Kolluri


                                   /s/ C. Richard Kramlich
                                   --------------------------
                                   C. Richard Kramlich


                                   /s/ Charles M. Linehan
                                   --------------------------
                                   Charles M. Linehan


                                   /s/ Peter T. Morris
                                   --------------------------
                                   Peter T. Morris


                                   /s/ John M. Nehra
                                   --------------------------
                                   John M. Nehra


                                   /s/ Charles W. Newhall III
                                   --------------------------
                                   Charles W. Newhall III


                                   /s/ Jason R. Nunn
                                   --------------------------
                                   Jason R. Nunn


                                   /s/ Mark W. Perry
                                   --------------------------
                                   Mark W. Perry


                                   /s/ Michael Raab
                                   --------------------------
                                   Michael Raab


                                   /s/ Scott D. Sandell
                                   --------------------------
                                   Scott D. Sandell


                                   /s/ A. Brooke Seawell
                                   --------------------------
                                   A. Brooke Seawell


                                   /s/ Eugene A. Trainor III
                                   --------------------------
                                   Eugene A. Trainor III


                               Page 29 of 30 pages

<PAGE>
===================                                          ===================
CUSIP NO. 03152W109                   13D                    PAGE 30 OF 30 PAGES
===================                                          ===================


                                   /s/ Sigrid Van Bladel
                                   --------------------------
                                   Sigrid Van Bladel


                                   /s/ Ravi Viswanathan
                                   --------------------------
                                   Ravi Viswanathan


                                   /s/ Harry Weller
                                   --------------------------
                                   Harry Weller




























                               Page 30 of 30 pages