Insider Transactions
| Date | Name | Title | Type | Filing | Shares Traded | Price Range | Total Held |
|---|---|---|---|---|---|---|---|
| Sep 18, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 11 | $16.00 | 66,335 | |
| Sep 18, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 108 | $14.02 | 66,227 | |
| Sep 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 5,870 | $17.06 | 1,767,651 | |
| Sep 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 4,858 | $15.77 | 1,762,793 | |
| Sep 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 219 | $17.07 | 66,008 | |
| Sep 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 182 | $15.77 | 65,826 | |
| Sep 22, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 2,726 | $16.02 | 1,760,067 | |
| Sep 22, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 103 | $16.02 | 65,723 | |
| Sep 29, 2008 | Senior VP, Drug Development | Open market or private sale of non-derivative or derivative security | Form 4 | 2,300 | $15.03 | 51,816 | |
| Sep 29, 2008 | Senior VP, Drug Development | Open market or private sale of non-derivative or derivative security | Form 4 | 200 | $16.23 | 51,616 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.