Insider Transactions
| Date | Name | Title | Type | Filing | Shares Traded | Price Range | Total Held |
|---|---|---|---|---|---|---|---|
| Aug 18, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 63 | $15.45 | 68,849 | |
| Aug 18, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 45 | $14.82 | 68,804 | |
| Aug 18, 2008 | VP, Medical Affairs | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | Form 4 | 1,401 | $0.64 | 1,553 | |
| Aug 18, 2008 | VP, Medical Affairs | Open market or private sale of non-derivative or derivative security | Form 4 | 1,401 | $15.11 | 152 | |
| Aug 18, 2008 | VP, Medical Affairs | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 | Form 4 | 1,401 | -- | 22,237 | |
| Aug 18, 2008 | Chief Operating Officer | Open market or private sale of non-derivative or derivative security | Form 4 | 2,700 | $15.02 | 53,749 | |
| Aug 18, 2008 | Chief Operating Officer | Open market or private sale of non-derivative or derivative security | Form 4 | 800 | $16.04 | 52,949 | |
| Aug 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 2,892 | $13.56 | 1,839,652 | |
| Aug 19, 2008 | Director | Open market or private sale of non-derivative or derivative security | Form 4 | 108 | $13.56 | 68,696 | |
| Aug 19, 2008 | Chief Operating Officer | Open market or private sale of non-derivative or derivative security | Form 4 | 3,800 | $13.71 | 49,149 |
* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.